Childhood Bronchiectasis : A Review
نویسنده
چکیده
More than two decades ago, bronchiectasis unrelated to cystic fibrosis (CF) was termed “Orphan disease”, because it had become an uncommon clinical entity among children in the developed world. It is more common among children in lower socioeconomic classes and in developing countries, due to more frequent recurrent respiratory infections, environmental airway irritants, poor immunization, and malnutrition. The pathophysiology includes airway inflammation, mucous production, and regional airway obstruction, but the reasons some children develop bronchiectasis while other do not is not clear. Public measures aimed at improving living conditions for children and prevention of respiratory infections with anti-viral vaccines will have a good impact on childhood bronchiectasis than medical treatment.
منابع مشابه
The etiologies of non-CF bronchiectasis in childhood: a systematic review of 989 subjects
BACKGROUND While cystic fibrosis (CF) is the most common cause of bronchiectasis in childhood, non-CF bronchiectasis is associated with a wide variety of disorders. The objective of this study was to determine the relative prevalence and specific etiologies on non-CF bronchiectasis in childhood. METHODS EMBASE, Medline, OVID Cochrane Reviews, Directory of Open Access Journals, Open Science Di...
متن کاملNon-cystic-fibrosis bronchiectasis in children: a persisting problem in developing countries.
BACKGROUND Non-cystic-fibrosis (non-CF) bronchiectasis in childhood is still one of the most common causes of childhood morbidity in developing countries. The management of these patients remains problematic, and there are few studies of long-term outcome. OBJECTIVE The aim of this retrospective study was to define the general characteristics, underlying causative factors and long-term follow...
متن کاملThe Role of Macrolides in Childhood Non-Cystic Fibrosis-Related Bronchiectasis
Non-cystic fibrosis-related bronchiectasis is a chronic inflammatory lung disease, which is regarded as an "orphan" lung disease, with little research devoted to the study of this condition. Bronchiectasis results in impaired quality of life and mortality if left untreated. The tools available in the armamentarium for the management of bronchiectasis entail antibiotic therapy traditionally used...
متن کاملEfficiency and safety of surgical intervention to patients with Non-Cystic Fibrosis bronchiectasis: a meta-analysis
No quantitative systematic review was found to report the efficiency and safety of surgical resection in the management of non-cystic fibrosis (non-CF) bronchiectasis. We therefore conducted a meta-analysis to assess the effects of operative intervention to patients with non-CF bronchiectasis. PubMed, the Cochrane library and Web of Science databases were searched up to July 8th, 2015. The pool...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2006